Article
rpoB Gene mutations and molecular characterization of rifampin-resistant Mycobacterium tuberculosis isolates from Shandong Province, China.
Journal of clinical microbiology - 1 Sept 2006
Ma Xin, Wang Haiying, Deng Yunfeng, Liu Zhimin, Xu Yong, Pan Xi, Musser James M, Graviss Edward A
Abstract excerpt
Sixty rifampin (RIF)-resistant and 75 RIF-susceptible Mycobacterium tuberculosis isolates from Shandong Province, China, were analyzed for rpoB gene mutations and genotyped. Mycobacterial interspersed repetitive unit (MIRU) genotype 223325173533 was overrepresented among RIF-resistant isolates. MIRU combined with IS6110 restriction fragment length polymorphism analysis as the second-line genotyping method may...
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