Article
Analysis of candidate genes on chromosome 2 in oral cleft case-parent trios from three populations.
Human genetics - 1 Nov 2006
Beaty T H, Hetmanski J B, Fallin M D, Park J W, Sull J W, McIntosh I, Liang K Y, Vanderkolk C A, Redett R J, Boyadjiev S A, Jabs E W, Chong S S, Cheah F S H, Wu-Chou Y H, Chen P K, Chiu Y F, Yeow V, Ng I S L, Cheng J, Huang S, Ye X, Wang H, Ingersoll R, Scott A F
Abstract excerpt
Isolated oral clefts, including cleft lip with/without cleft palate (CL/P) and cleft palate (CP), have a complex and heterogeneous etiology. Case-parent trios from three populations were used to study genes spanning chromosome 2, where single nucleotide polymorphic (SNP) markers were analyzed individually and as haplotypes. Case-parent trios from three populations (74 from Maryland, 64 from Singapore and 95 from...
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