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Article

Association between genes on chromosome 4p16 and non-syndromic oral clefts in four populations.

European journal of human genetics : EJHG - 1 Jun 2010

Ingersoll Roxann G, Hetmanski Jacqueline, Park Ji-Wan, Fallin M Daniele, McIntosh Iain, Wu-Chou Yah-Huei, Chen Philip K, Yeow Vincent, Chong Samuel S, Cheah Felicia, Sull Jae Woong, Jee Sun Ha, Wang Hong, Wu Tao, Murray Tanda, Huang Shangzhi, Ye Xiaoqian, Jabs Ethylin Wang, Redett Richard, Raymond Gerald, Scott Alan F, Beaty Terri H

Abstract excerpt

Isolated cleft lip with or without cleft palate and cleft palate are among the most common human birth defects. Several candidate gene studies on MSX1 have shown significant association between markers in MSX1 and risk of oral clefts, and re-sequencing studies have identified multiple mutations i...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 20087401
DOI: 10.1038/ejhg.2009.228
PMCID: PMC2874614

Genes

MSX1
EVC
EVC2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20087401-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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