Differential regulation of endogenous and transduced beta-globin genes during infection of erythroid cells with a herpes simplex virus type 1 recombinant.

Abstract excerpt

We infected murine erythroleukemia cells with a nondefective herpes simplex virus (HSV) type 1 recombinant bearing the rabbit beta-globin gene under the control of its own promoter, in order to compare the regulation of a cellular gene residing in the viral genome to that of its active endogenous...

Topics

• Animals
• Base Sequence
• Cell Line
• Cell Nucleus
• Cell Transformation, Viral
• Cycloheximide
• Dactinomycin
• Gene Expression Regulation
• Gene Expression Regulation, Viral
• Genes
• Globins
• Kinetics
• Mice
• Molecular Sequence Data
• Mutation
• Oligonucleotide Probes
• RNA
• Rabbits