Article
Expression of the human gamma-globin gene after retroviral transfer to transformed erythroid cells.
Biochemistry - 8 May 1990
Rixon M W, Harris E A, Gelinas R E
Abstract excerpt
Regulation of the human fetal (gamma) globin gene and a series of mutant gamma-globin genes was studied after retroviral transfer into erythroid cells with fetal or adult patterns of endogenous globin gene expression. Steady-state RNA from a virally transferred A gamma-globin gene with a normal promoter increased after induction of erythroid maturation of murine erythroleukemia cells and comprised from 2% to 23%...
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