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Article

Tumour-cell fusion as a source of myeloid traits in cancer.

The Lancet. Oncology - 1 Dec 2005

Pawelek John M

Abstract excerpt

Malignant cells express molecular pathways that are also expressed by myeloid cells. Such behaviour is associated with loss of homotypic adhesion between cells, changes in the cellular matrix, induction of angiogenesis, motility, chemotaxis, and several immune-signalling pathways. The overlap between malignant cells and myeloid cells could be explained by one mechanism: fusion of myeloid cells and tumour cells,...

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PMID: 16321767
DOI: 10.1016/S1470-2045(05)70466-6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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