Article
Reorganisation of the microtubular cytoskeleton by embryonic microtubule-associated protein 2 (MAP2c).
Development (Cambridge, England) - 1 Dec 1992
Weisshaar B, Doll T, Matus A
Abstract excerpt
Microtubule-associated protein 2c (MAP2c) is one of a set of embryonic MAP forms that are expressed during neuronal differentiation in the developing nervous system. We have investigated its mode of action by expressing recombinant protein in non-neuronal cell lines using cell cDNA transfection techniques. At every level of expression, all the MAP2c was bound to cellular microtubules. At low MAP2c levels, the...
Topics
- Animals
- Calcium-Calmodulin-Dependent Protein Kinases
- Cytoskeleton
- Microscopy, Electron
- Microtubules
- Nervous System
- Phenotype
- Protein Kinases
- Rats
- Transfection