Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mechanism of oligomerisation of cyclase-associated protein from Dictyostelium discoideum in solution.

Journal of molecular biology - 6 Oct 2006

Yusof Adlina Mohd, Jaenicke Elmar, Pedersen Jan Skov, Noegel Angelika A, Schleicher Michael, Hofmann Andreas

Abstract excerpt

Cyclase-associated protein (CAP) is a highly conserved modular protein implicated in the regulation of actin filament dynamics and a variety of developmental and morphological processes. The protein exists as a high molecular weight complex in cell extracts and purified protein possesses a high tendency to aggregate, a major obstacle for crystallisation. Using a mutagenesis approach, we show that two structural...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromatography, Gel
Share to Circular Dichroism

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Crystallography

Share to Dictyostelium

Share to Models, Chemical

Share to Protein Denaturation

Share to Solutions

Source

Identifiers

PMID: 16949609
DOI: 10.1016/j.jmb.2006.08.008

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mechanism of oligomerisation of cyclase-associated protein from Dictyostelium discoideum in solution.PMID 16949609Read ↗

A novel Dictyostelium discoideum gene required for cAMP-dependent cell aggregation.Semantic proximity Read ↗

Dimerization of mammalian adenylate cyclases.Semantic proximity Read ↗

Microarray phenotyping places cyclase associated protein CAP at the crossroad of signaling pathways reorganizing the actin cytoskeleton in Dictyostelium.Semantic proximity Read ↗

The Dictyostelium homologue of mammalian soluble adenylyl cyclase encodes a guanylyl cyclase.Semantic proximity Read ↗

Supramolecular complexes of GCAP1: towards the development of effective biologics for inherited retinal dystrophiesSemantic proximity Read ↗

CcdA chaperones CcdB against irreversible misfolding and aggregation via a cotranslational folding mechanism.Semantic proximity Read ↗

Regulation of adenylyl cyclases by a region outside the minimally functional cytoplasmic domains.Semantic proximity Read ↗

Ege A, a novel C2 domain containing protein, is essential for GPCR-mediated gene expression in dictyostelium.Semantic proximity Read ↗

Critical roles of CTP synthase N-terminal in cytoophidium assembly.Semantic proximity Read ↗

Mutation in the β-hairpin of the Bordetella pertussis adenylate cyclase toxin modulates N-lobe conformation in calmodulin.Semantic proximity Read ↗

Conserved structural and functional properties of D-domain containing redox-active and -inactive protein disulfide isomerase-related protein chaperones.Semantic proximity Read ↗

Mechanism of Epac activation: structural and functional analyses of Epac2 hinge mutants with constitutive and reduced activities.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.