Article
Quantitative trait loci for carbohydrate and total energy intake on mouse chromosome 17: congenic strain confirmation and candidate gene analyses (Glo1, Glp1r).
American journal of physiology. Regulatory, integrative and comparative physiology - 1 Jan 2007
Kumar K Ganesh, Poole Angela C, York Barbara, Volaufova Julia, Zuberi Aamir, Richards Brenda K Smith
Abstract excerpt
Quantitative trait loci (QTL) for carbohydrate (Mnic1) and total energy (Kcal2) intake on proximal mouse chromosome 17 were identified previously from a C57BL/6J (B6) X CAST/Ei (CAST) intercross. Here we report that a new congenic strain developed in our laboratory has confirmed this complex locus by recapitulating the original linked phenotypes: B6.CAST-17 homozygous congenic mice consumed more carbohydrate...
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