Article
Genetic variation in Glp1r expression influences the rate of gastric emptying in mice.
American journal of physiology. Regulatory, integrative and comparative physiology - 1 Feb 2008
Kumar K Ganesh, Byerley Lauri O, Volaufova Julia, Drucker Daniel J, Churchill Gary A, Li Renhua, York Barbara, Zuberi Aamir, Richards Brenda K Smith
Abstract excerpt
We demonstrated previously that food intake traits map to a quantitative trait locus (QTL) on proximal chromosome 17, which encompasses Glp1r (glucagon-like peptide 1 receptor), encoding an important modulator of gastric emptying. We then confirmed this QTL in a B6.CAST-17 congenic strain that consumed 27% more carbohydrate and 17% more total calories, yet similar fat calories, per body weight compared with the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
