Article
Nonimmune immunoglobulin binding and multiple adhesion characterize <i>Plasmodium falciparum</i> -infected erythrocytes of placental origin
31 Aug 2006
Abstract excerpt
The harmful effects of pregnancy-associated malaria (PAM) are engendered by the heavy sequestration of Plasmodium falciparum-parasitized RBCs in the placenta. It is well documented that this process is mediated by interactions of parasite-encoded variant surface antigens and placental receptors. A P. falciparum erythrocyte membrane protein 1 variant, VAR2CSA, and the placental receptor chondroitin sulfate A (CSA)...
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