Article
Nonspecific immunoglobulin M binding and chondroitin sulfate A binding are linked phenotypes of Plasmodium falciparum isolates implicated in malaria during pregnancy.
Infection and immunity - 1 Aug 2003
Creasey Alison M, Staalsoe Trine, Raza Ahmed, Arnot David E, Rowe J Alexandra
Abstract excerpt
Binding of immunoglobulin M (IgM) antibodies from normal human serum to the surface of Plasmodium falciparum-infected red blood cells (iRBC) has previously been demonstrated only in parasites that form rosettes with uninfected red cells. We show that natural, nonspecific IgM but not IgG, IgA, IgD...
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