Article
Influence of pepsinogen gene polymorphisms on serum pepsinogen.
Annals of human genetics - 1 Mar 1997
Yamagata Z, Zhang Y, Shinozaki S, Miyamura T, Iijima S, Asaka A, Kobayashi K
Abstract excerpt
We identified pepsinogen C (PGC) gene polymorphisms by means of PCR, which amplified DNA in the region within the intron between exons 7 and 8, and by 6% polyacrylamide gel electrophoresis. Six alleles were found in a Japanese population. The frequencies of these alleles in 408 unrelated Japanese individuals were 0.074, 0.026, 0.335, 0.237, 0.016 and 0.314, respectively. The serum pepsinogen II level...
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