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Article

Overall survival in women with breast cancer: the influence of pepsinogen C gene polymorphism.

DNA and cell biology - 1 Jun 2008

Pinto-Correia Ana L, Pinto Daniela, Pereira Deolinda, Rodrigues Helena, de Sousa Joaquim Abreu, Sousa Hugo, Sousa Berta, Sousa Susana, Lopes Carlos, Medeiros Rui

Abstract excerpt

We aimed to study the role of an insertion/deletion polymorphism in the Pepsinogen C (PGC) gene in the clinical outcome of 172 breast cancer patients. The six polymorphic alleles were amplified using PCR. Our results indicate that patients carrying the allele 6 present a higher 5-year survival mean (83.4% of 6 allele carriers were alive at 5 years vs. only 68.6% of noncarriers, p=0.001), suggesting a role for...

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Identifiers

PMID: 18447628
DOI: 10.1089/dna.2007.0713

Genes

PGC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

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