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Article

E-selectin genotypes and risk of type 2 diabetes in women.

Obesity research - 1 Mar 2005

Meigs James B, Hu Frank B, Perhanidis Jessica S, Hunter David, Rifai Nader, Manson Joann E

Abstract excerpt

Endothelial dysfunction increases risk for type 2 diabetes. We examined whether variation in the gene for E-selectin (SELE), a biomarker of endothelial dysfunction, was associated with levels of E-selectin or diabetes quantitative traits (including fasting levels of insulin and hemoglobin A(1c)) in 719 nondiabetic participants of the Nurses' Health Study or with risk of diabetes in 602 incident (over 10 years of...

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Source

Identifiers

PMID: 15833936
DOI: 10.1038/oby.2005.54

Genes

SELE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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E-selectin genotypes and risk of type 2 diabetes in women.PMID 15833936Read ↗

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P-selectin gene genotypes or haplotypes and cardiovascular complications in type 2 diabetes mellitus.Semantic proximity Read ↗

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Common variants of the endothelial nitric oxide synthase gene and the risk of coronary heart disease among U.S. diabetic men.Semantic proximity Read ↗

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Putative functional non-coding polymorphisms in SELP significantly modulate sP-selectin levels, arterial stiffness and type 2 diabetes mellitus susceptibility.Semantic proximity Read ↗

Endothelial nitric oxide synthase polymorphisms are associated with type 2 diabetes and the insulin resistance syndrome.Semantic proximity Read ↗

Detection of a large deletion in the P-selectin (SELP) gene.Semantic proximity Read ↗

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