Article
Screening for mutations of the ferritin light and heavy genes in Parkinson's disease patients with hyperechogenicity of the substantia nigra.
Neuroscience letters - 27 Nov 2003
Felletschin Bettina, Bauer Peter, Walter Uwe, Behnke Stephanie, Spiegel Jörg, Csoti Ilona, Sommer Ulrike, Zeiler Björn, Becker Georg, Riess Olaf, Berg Daniela
Abstract excerpt
Recently, an insertional mutation in the ferritin-L gene was reported in some patients with familial basal ganglia degeneration, which, however, could not be detected in another Parkinson's disease (PD) population. We investigated 186 PD patients, in whom an increased amount of iron of the substantia nigra (SN) was priorly identified by transcranial ultrasound, for mutations of the whole coding region of...
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