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Article

Substantia nigra echogenicity is associated with serum ferritin, gender and iron-related genes in Parkinson's disease.

Scientific reports - 26 May 2020

Li Kai, Ge Yi-Lun, Gu Chen-Chen, Zhang Jin-Ru, Jin Hong, Li Jiao, Cheng Xiao-Yu, Yang Ya-Ping, Wang Fen, Zhang Ying-Chun, Chen Jing, Mao Cheng-Jie, Liu Chun-Feng

Abstract excerpt

Substantia nigra (SN) hyperechogenicity is present in most Parkinson's disease (PD) cases but is occasionally absent in some. To date, age, gender, disease severity, and other factors have been reported to be associated with SN hyperechogenicity in PD. Previous studies have discovered that excess iron deposition in the SN underlies its hyperechogenicity in PD, which may also indicate the involvement of genes...

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Identifiers

PMID: 32457446
DOI: 10.1038/s41598-020-65537-5
PMCID: PMC7250839

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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