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Article

Rare genetic variants in GATA transcription factors in patients with hypertrophic cardiomyopathy.

Journal of investigative medicine : the official publication of the American Federation for Clinical Research - 1 Jun 2017

Alonso-Montes Cristina, Rodríguez-Reguero Julián, Martín María, Gómez Juan, Coto Eliecer, Naves-Díaz Manuel, Morís César, Cannata-Andía Jorge B, Rodríguez Isabel

Abstract excerpt

Hypertrophic cardiomyopathy (HCM) is a very heterogeneous disease. Although primarily caused by mutations in genes encoding sarcomeric proteins, other genes might explain that heterogeneity. Potential candidate genes are GATA transcription factors that regulate the expression of proteins associated with HCM. Exons of GATA2, GATA4, and GATA6 genes were sequenced in 212 patients with unrelated HCM previously...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 28381408
DOI: 10.1136/jim-2016-000364

Genes

GATA2
GATA4
GATA6

Variants

rs370588269

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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