Article
[Biological significance of E-cadherin in an inflammatory breast carcinoma cell line].
Zhonghua zhong liu za zhi [Chinese journal of oncology] - 1 Jan 2006
Dong Hui-ming, Liu Gang, Wu Jiong, Lu Jin-song, Luo Jian-min, Shen Zhen-zhou, Shao Zhi-min
Abstract excerpt
OBJECTIVE: To investigate the effects of E-cadherin on the biologic behavior of SUM149, an inflammatory breast cancer cell line. METHODS: SUM149 cells were transfected with dominant-negative mutant E-cadherin expressing plasmid. The positive clones with higher expression of dominant-negative E-cadherin mutant were identified by RT-PCR and fluorescent flow cytometry method. The differences in cell growth,...
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