Article
E-cadherin expression: a counterbalance for cancer cell invasion.
Bulletin du cancer - 1 Jan 1992
Mareel M, Vleminckx K, Vermeulen S, Bracke M, Van Roy F
Abstract excerpt
Invasion, eventually leading to metastasis, is presented as the result of a balance between the activation of 2 sets of genes, coined i+ (invasion promotor) and i- (invasion suppressor) genes. Experiments in vitro have indicated that the homotypic homophilic epithelial cell--cell adhesion molecul...
Topics
- Animals
- Cadherins
- Cell Transformation, Neoplastic
- Gene Expression Regulation, Neoplastic
- Humans
- Mice
- Mice, Nude
- Neoplasm Invasiveness
- Neoplasms, Experimental
- Phenotype