Article
Polymorphisms in the IL-4 and IL-4R [alpha] genes and allergic asthma.
Clinical chemistry and laboratory medicine - 1 Jul 2003
Cui Tianpen, Wu Jianmin, Pan Shixiu, Xie Jungang
Abstract excerpt
Allergic asthma is caused by genetic and environmental factors that interact to determine disease susceptibility and severity. Several lines of evidence suggest that the interleukin (IL-4 gene and the IL-4-receptor alpha (IL-4Ralpha) gene are involved in the development of atopic diseases. We sought to determine whether two polymorphism sites in IL-4 and IL-4Ralpha chain were associated with allergic asthma in a...
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