Article
Analysis of the effect of aluminum in drinking water and transferrin C2 allele on Alzheimer's disease.
European journal of neurology - 1 Sept 2006
Rondeau V, Iron A, Letenneur L, Commenges D, Duchêne F, Arveiler B, Dartigues J-F
Abstract excerpt
Although highly controversial, the hypothesis of a link between aluminum (Al) in drinking water and Alzheimer's disease (AD) has been supported by several epidemiological studies. Transferrin (Tf) is a major transport protein for both iron and Al. Moreover, it has been demonstrated that defective binding of iron and Al to the Tf variant C2 could be present in AD. Individuals carrying the Tf C2 allele might...
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