Article
Association of transferrin C2 allele with late-onset Alzheimer's disease.
Human genetics - 1 Dec 1997
Namekata K, Imagawa M, Terashi A, Ohta S, Oyama F, Ihara Y
Abstract excerpt
Transferrin (Tf), an iron-transporting protein, has many variants, but C1 and C2 variants account for the majority of the population in all races. Since Tf is reported to be immunocytochemically detectable in senile plaques in Alzheimer's disease (AD), we have examined the Tf allele frequency among AD patients. The C2 allele frequency in late-onset AD patients is significantly higher than that in age-matched...
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