Genetic screening for functionality of bacterial potassium channel mutants using K+ uptake-deficient Escherichia coli.

Abstract excerpt

Potassium channels play an essential role in a wide range of biological processes, including cell volume regulation and the maintenance and control of electrical signals. With the advent of the structural era of ion channel biology, it has become critical to learn more about the functional properties of the prokaryotic channels, and this is the area in which genetic screens have become an increasingly useful...

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