Article
Functional studies of the chromosome 3p21.3 candidate tumor suppressor gene BLU/ZMYND10 in nasopharyngeal carcinoma.
International journal of cancer - 15 Dec 2006
Yau Wing Lung, Lung Hong Lok, Zabarovsky Eugene R, Lerman Michael I, Sham Jonathan Shun-Tong, Chua Daniel Tsin-Tien, Tsao Sai Wah, Stanbridge Eric J, Lung Maria Li
Abstract excerpt
Chromosome 3p plays an important role in tumorigenesis in many cancers, including nasopharyngeal carcinoma (NPC). We have previously shown chromosome 3p can suppress tumor growth in vivo by using the monochromosome transfer approach, which indicated the chromosome 3p21.3 region was critical for tumor suppression. BLU/ZMYND10 is one of the candidate tumor suppressor genes mapping in the 3p21.3 critical region and...
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