Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Differential Regulation of Iron- and Manganese-Specific MtsABC and Heme-Specific HtsABC Transporters by the Metalloregulator MtsR of Group A <i>Streptococcus</i>

22 Aug 2006

Abstract excerpt

The genome of the human pathogen group A Streptococcus (GAS) encodes the transporters MtsABC, FtsABCD, and HtsABC to take up ferric and manganese ions, ferric ferrichrome, and heme, respectively. The GAS genome also encodes two metalloregulators PerR and MtsR. To understand the regulation of the expression of these transporters, the mtsR and perR deletion mutants of a GAS serotype M1 strain were generated, and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antimicrobial Resistance in Staphylococcus
Share to Neonatal and Maternal Infections
Share to Streptococcal Infections and Treatments

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 16926405
DOI: 10.1128/iai.00176-06

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Differential Regulation of Iron- and Manganese-Specific MtsABC and Heme-Specific HtsABC Transporters by the Metalloregulator MtsR of Group A <i>Streptococcus</i>PMID 16926405Read ↗

Metal sensing and regulation of adaptive responses to manganese limitation by MtsR is critical for group A streptococcus virulence.Semantic proximity Read ↗

Iron Efflux by PmtA Is Critical for Oxidative Stress Resistance and Contributes Significantly to Group A Streptococcus VirulenceSemantic proximity Read ↗

MtsR is a dual regulator that controls virulence genes and metabolic functions in addition to metal homeostasis in the group A streptococcusSemantic proximity Read ↗

Manganese Homeostasis in Group A Streptococcus Is Critical for Resistance to Oxidative Stress and VirulenceSemantic proximity Read ↗

The PerR-Regulated P1B-4-Type ATPase (PmtA) Acts as a Ferrous Iron Efflux Pump in Streptococcus pyogenes.Semantic proximity Read ↗

Cellular management of Zinc in group B <i>Streptococcus</i> supports bacterial resistance against metal intoxication and promotes disseminated infectionSemantic proximity Read ↗

Metal Homeostasis in Pathogenic StreptococciSemantic proximity Read ↗

Crystal Structure and Metal Binding Properties of the Lipoprotein MtsA, Responsible for Iron Transport in <i>Streptococcus pyogenes</i>Semantic proximity Read ↗

Transcriptomic Analysis of <em>Streptococcus suis</em> in Response to Ferrous Iron and Cobalt ToxicitySemantic proximity Read ↗

Identification and characterization of a Streptococcus pyogenes ABC transporter with multiple specificity for metal cationsSemantic proximity Read ↗

A role for the DtxR family of metalloregulators in gram‐positive pathogenesisSemantic proximity Read ↗

PmtA functions as a ferrous iron and cobalt efflux pump in Streptococcus suisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.