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Article

Staphylococcus aureus mutants with increased lysostaphin resistance.

Journal of bacteriology - 1 Sept 2006

Gründling Angelika, Missiakas Dominique M, Schneewind Olaf

Abstract excerpt

Staphylococcus simulans secretes lysostaphin, a bacteriolytic enzyme that specifically binds to the cell wall envelope of Staphylococcus aureus and cleaves the pentaglycine cross bridges of peptidoglycan, thereby killing staphylococci. The study of S. aureus mutants with resistance to lysostaphin-mediated killing has revealed biosynthetic pathways for cell wall assembly. To identify additional genes involved in...

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Identifiers

PMID: 16923896
DOI: 10.1128/JB.00457-06
PMCID: PMC1595375

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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