Article
Structural characterization of an abnormally cross-linked muropeptide dimer that is accumulated in the peptidoglycan of methicillin- and cefotaxime-resistant mutants of Staphylococcus aureus.
The Journal of biological chemistry - 14 Nov 1997
Boneca I G, Xu N, Gage D A, de Jonge B L, Tomasz A
Abstract excerpt
Laboratory mutants of Staphylococcus aureus strain ATCC 8325 (27S) selected for increased minimal inhibitory concentration (MIC) values to methicillin and cefotaxime showed increased rates of cell wall turnover and detergent-induced autolysis in virtual parallel with the increasing MIC for the antibiotic. Also in parallel with the increasing MICs for the particular antibiotic used in the selection was the gradual...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.