Article
Suppression of glycopeptide resistance in a highly teicoplanin-resistant mutant of Staphylococcus aureus by transposon inactivation of genes involved in cell wall synthesis.
Microbial drug resistance (Larchmont, N.Y.) - 1 Jan 1998
Sieradzki K, Tomasz A
Abstract excerpt
The teicoplanin-resistant laboratory mutant TNM of Staphylococcus aureus strain COL (minimal inhibitory concentration for teicoplanin increased from 3 to 200 microg/ml) produced an abnormal peptidoglycan in which the proportion of cross-linked oligomeric muropeptides (pentameric and higher than pentameric species), representing approximately 60% of all muropeptide species in the parental strain, was reduced to...
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