Article
Suppression of glycopeptide resistance in a highly teicoplanin-resistant mutant of Staphylococcus aureus by transposon inactivation of genes involved in cell wall synthesis.
Microbial drug resistance (Larchmont, N.Y.) - 1 Jan 1998
Sieradzki K, Tomasz A
Abstract excerpt
The teicoplanin-resistant laboratory mutant TNM of Staphylococcus aureus strain COL (minimal inhibitory concentration for teicoplanin increased from 3 to 200 microg/ml) produced an abnormal peptidoglycan in which the proportion of cross-linked oligomeric muropeptides (pentameric and higher than p...
Topics
- Anti-Bacterial Agents
- Cell Wall
- DNA Transposable Elements
- Detergents
- Drug Resistance, Microbial
- Genes, Bacterial
- Genes, Regulator
- Microscopy, Electron
- Mutation
- Peptidoglycan
- Staphylococcus aureus
- Teicoplanin
- Vancomycin