Article
Applications of computational algorithm tools to identify functional SNPs in cytokine genes.
Cytokine - 1 Jul 2006
Shen Jie, Deininger Prescott L, Zhao Hua
Abstract excerpt
Understanding the functions of single nucleotide polymorphisms (SNPs) can greatly help to understand the genetics of the human phenotype variation and especially the genetic basis of human complex diseases. However, how to identify functional SNPs from a pool containing both functional and neutral SNPs is challenging. In this study, we analyzed the genetic variations that can alter the expression and function of...
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