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Article

Polymorphisms at exon 4 of p53 and the susceptibility to herpesvirus types 6 and 1 infection in renal transplant recipients.

Transplant international : official journal of the European Society for Organ Transplantation - 1 Sept 2006

Leite Janaína L, Manfrinatto Juliana A, Mazzali Marilda, Ward Laura S

Abstract excerpt

In order to replicate their own genome in the host nucleus, herpesviruses have to overcome the barrier presented by p53 gene. Variants of codon 72 and codon 47 of exon four decrease the ability of p53 to induce apoptosis. In order to investigate the influence of this germline inheritance on the susceptibility to herpesvirus type 6 (HHV6) and 1 (HHV1) infection, we examined 78 renal transplant recipients and 151...

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Source

Identifiers

PMID: 16918534
DOI: 10.1111/j.1432-2277.2006.00346.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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