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Article

Integrated molecular profiling of SOD2 expression in multiple myeloma

27 Dec 2006

Abstract excerpt

Reactive oxygen species are known to be involved in several cellular processes, including cell signaling. SOD2 is a key enzyme in the conversion of reactive oxygen species and has been implicated in a host of disease states, including cancer. Using an integrated, whole-cell approach encompassing epigenetics, genomics, and proteomics, we have defined the role of SOD2 in multiple myeloma. We show that the SOD2...

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PMID: 17192397
DOI: 10.1182/blood-2006-07-035162

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