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Article

Global methylation analysis identifies prognostically important epigenetically inactivated tumor suppressor genes in multiple myeloma.

Blood - 11 Jul 2013

Kaiser Martin F, Johnson David C, Wu Ping, Walker Brian A, Brioli Annamaria, Mirabella Fabio, Wardell Christopher P, Melchor Lorenzo, Davies Faith E, Morgan Gareth J

Abstract excerpt

Outcome in multiple myeloma is highly variable and a better understanding of the factors that influence disease biology is essential to understand and predict behavior in individual patients. In the present study, we analyzed combined genomewide DNA methylation and gene expression data of patients treated in the Medical Research Council Myeloma IX trial. We used these data to identify epigenetically repressed...

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Source

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Identifiers

PMID: 23699600
DOI: 10.1182/blood-2013-03-487884
PMCID: PMC3709654

Genes

GPX3
RBP1
SPARC
TGFBI

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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