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Investigating disease susceptibility and the negative correlation of schizophrenia and rheumatoid arthritis focusing on MIF and CD14 gene polymorphisms.

Psychiatry research - 30 Sept 2006

de la Fontaine Larissa, Schwarz Markus J, Riedel Michael, Dehning Sandra, Douhet Anette, Spellmann Ilja, Kleindienst Nikolaus, Zill Peter, Plischke Herbert, Gruber Rudolf, Müller Norbert

Abstract excerpt

Schizophrenia and rheumatoid arthritis (RA) are both chronic diseases with an estimated genetic component of 60%. While RA is a well-known autoimmune inflammatory joint disease, recent data point to an active immune process also being involved in schizophrenia. Several studies confirmed the negative association between schizophrenia and RA, indicating genetic factors that predispose to the one disorder, while...

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Identifiers

PMID: 16916546
DOI: 10.1016/j.psychres.2006.01.006

Genes

MIF

Variants

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Source receipt: pubmed, retrieved 7 Sept 2026.

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