Article
Lack of association of the CD14/C -- 159T polymorphism with susceptibility and progression parameters in Turkish multiple sclerosis patients.
Journal of neuroimmunology - 15 Sept 2012
Kurne Asli, Sayat Guliz, Aydin Omer Faruk, Turgutoglu Nihan, Terzi Murat, Sackesen Cansin, Karabulut Erdem, Karabudak Rana
Abstract excerpt
Soluble (s) CD14, being a receptor for lipopolysaccharides (LPSs) may inhibit LPS-triggered apoptosis and T lymphocyte proliferation. C to T exchange at position -159 in the promoter region of the CD14 gene might lead to higher sCD14 levels. Limited number of groups have studied whether these polymorphisms might influence the development of organ specific autoimmunity and whether higher CD14 levels are associated...
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