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Article

Increased serum levels and promoter polymorphisms of macrophage migration inhibitory factor in schizophrenia.

Progress in neuro-psychopharmacology & biological psychiatry - 20 Apr 2018

Okazaki Satoshi, Hishimoto Akitoyo, Otsuka Ikuo, Watanabe Yuichiro, Numata Shusuke, Boku Shuken, Shimmyo Naofumi, Kinoshita Makoto, Inoue Emiko, Ohmori Tetsuro, Someya Toshiyuki, Sora Ichiro

Abstract excerpt

BACKGROUND: Numerous studies have suggested that an immune system imbalance plays an important role in schizophrenia. Macrophage migration inhibitory factor (MIF) is a pleiotropic cytokine. It plays multiple roles in various biological processes, including inflammation and neurogenesis. Furthermore, several exhaustive serum proteomic profiling studies have identified MIF as a potential biomarker of schizophrenia....

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Identifiers

PMID: 29305329
DOI: 10.1016/j.pnpbp.2018.01.001

Genes

MIF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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