Article
MCP-1 gene (SCYA2) and schizophrenia: a case-control association study.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Jan 2005
Mundo Emanuela, Altamura A Carlo, Vismara Serena, Zanardini Roberta, Bignotti Stefano, Randazzo Roberto, Montresor Claudio, Gennarelli Massimo
Abstract excerpt
Dysregulation of the inflammatory response system has been linked to the pathophysiology of schizophrenia. Abnormal levels of proinflammatory cytokines and their receptors have been found in peripheral blood and cerebrospinal fluid of schizophrenic patients, suggesting the presence of immune activation. Monocyte chemoattractant protein 1 (MCP-1) influences the expression of cytokines related to T helper...
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