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Article

An RNA gene expressed during cortical development evolved rapidly in humans.

Nature - 14 Sept 2006

Pollard Katherine S, Salama Sofie R, Lambert Nelle, Lambot Marie-Alexandra, Coppens Sandra, Pedersen Jakob S, Katzman Sol, King Bryan, Onodera Courtney, Siepel Adam, Kern Andrew D, Dehay Colette, Igel Haller, Ares Manuel, Vanderhaeghen Pierre, Haussler David

Abstract excerpt

The developmental and evolutionary mechanisms behind the emergence of human-specific brain features remain largely unknown. However, the recent ability to compare our genome to that of our closest relative, the chimpanzee, provides new avenues to link genetic and phenotypic changes in the evolution of the human brain. We devised a ranking of regions in the human genome that show significant evolutionary...

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Identifiers

PMID: 16915236
DOI: 10.1038/nature05113

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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