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Article

Phenotype-based identification of host genes required for replication of African swine fever virus.

Journal of virology - 1 Sept 2006

Chang Annie C Y, Zsak Laszlo, Feng Yanan, Mosseri Ronen, Lu Quan, Kowalski Paul, Zsak Aniko, Burrage Thomas G, Neilan John G, Kutish Gerald F, Lu Zhiqiang, Laegreid Will, Rock Daniel L, Cohen Stanley N

Abstract excerpt

African swine fever virus (ASFV) produces a fatal acute hemorrhagic fever in domesticated pigs that potentially is a worldwide economic threat. Using an expressed sequence tag (EST) library-based antisense method of random gene inactivation and a phenotypic screen for limitation of ASFV replication in cultured human cells, we identified six host genes whose cellular functions are required by ASFV. These included...

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Identifiers

PMID: 16912318
DOI: 10.1128/JVI.00475-06
PMCID: PMC1563864

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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