Article
Hepatitis B virus genotypes and precore/core-promoter mutations in Tunisian patients with chronic hepatitis B virus infection.
The Journal of infection - 1 Mar 2007
Ayed Khaled, Gorgi Yousr, Ayed-Jendoubi Saloua, Aouadi Houda, Sfar Imen, Najjar Tawfik, Ben Abdallah Taieb
Abstract excerpt
OBJECTIVE: The aim of this study was to determine the frequency of genotype and precore/core-promoter mutations in chronic hepatitis B virus (HBV) infected individuals in Tunisia. METHODS: We studied 164 Tunisian patients (38 HBeAg-positive and 126 HBeAg-negative) with chronic HBV infection. Genotypes and precore/core-promoter mutations were studied using Inno-LiPA and Multiplex-PCR and PCR-RFLP methodology....
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