Article
Silencing of stathmin induces tumor-suppressor function in breast cancer cell lines harboring mutant p53.
Oncogene - 15 Feb 2007
Alli E, Yang J-M, Hait W N
Abstract excerpt
Cancers harboring dominant-negative p53 mutations are often aggressive and difficult to treat. Direct attempts to restore wild-type p53 function have produced little clinical benefit. We investigated whether targeting a p53-target gene could induce certain tumor-suppressor characteristics. We fou...
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