Article
Downregulation of stathmin is involved in malignant phenotype reversion and cell apoptosis in esophageal squamous cell carcinoma.
Journal of surgical oncology - 1 Jun 2011
Wang Feng, Wang Liu-Xing, Li Sheng-Lei, Li Ke, He Wei, Liu Hong-Tao, Fan Qing-Xia
Abstract excerpt
BACKGROUND AND OBJECTIVES: Stathmin plays a critical role in the regulation of mitosis and mediates the development of malignant tumors. Here, we investigated the potential role of stathmin in cell cycle and apoptosis in esophageal squamous cell carcinoma (ESCC). METHODS: A stathmin short hairpin RNA (shRNA) plasmid was employed to downregulate stathmin expression in the ESCC cell line EC9706 cells. Cell...
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