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Article

A FoxO-Smad synexpression group in human keratinocytes.

Proceedings of the National Academy of Sciences of the United States of America - 22 Aug 2006

Gomis Roger R, Alarcón Claudio, He Wei, Wang Qiongqing, Seoane Joan, Lash Alex, Massagué Joan

Abstract excerpt

Transforming growth factor beta (TGF-beta) signals through activation of Smad transcription factors. Activated Smad proteins associate with different DNA-binding cofactors for the recognition and regulation of specific target genes. Members of the forkhead box O family (FoxO1, FoxO3, and FoxO4) play such a role in the induction of the cyclin-dependent kinase inhibitors p15Ink4b and p21Cip1. To delineate the...

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Source

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Identifiers

PMID: 16908841
DOI: 10.1073/pnas.0605333103
PMCID: PMC1568919

Genes

JAG1
LEMD3
OVOL1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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