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Article

SMAD4 Feedback Activates the Canonical TGF-β Family Signaling Pathways

16 Sept 2021

Abstract excerpt

TGF-β family signaling pathways, including TGF-β and BMP pathways, are widely involved in the regulation of health and diseases through downstream SMADs, which are also regulated by multiple validated mechanisms, such as genetic regulation, epigenetic regulation, and feedback regulation. However, it is still unclear whether R-SMADs or Co-SMAD can feedback regulate the TGF-β family signaling pathways in granulosa...

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PMID: 34576190
DOI: 10.3390/ijms221810024

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