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Article

Numerous high-risk epithelial lesions in familial breast cancer.

European journal of cancer (Oxford, England : 1990) - 1 Oct 2006

Hoogerbrugge N, Bult P, Bonenkamp J J, Ligtenberg M J L, Kiemeney L A, de Hullu J A, Boetes C, Niermeijer M F, Brunner H G

Abstract excerpt

PURPOSE: To assess the occurrence of high-risk epithelial lesions in women of breast cancer families with and without a BRCA mutation. PATIENTS AND METHODS: Prospective study of women at very high risk of breast cancer undergoing prophylactic mastectomy (68 BRCA1 mutation carriers, 14 BRCA2 mutation carriers and 24 non-BRCA mutation carriers). RESULTS: The prevalence of high-risk lesions is equal in women with a...

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Source

Identifiers

PMID: 16908132
DOI: 10.1016/j.ejca.2006.05.027

Genes

BRCA1
BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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