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Article

Epithelial lesions in prophylactic mastectomy specimens from women with BRCA mutations.

Cancer - 1 Apr 2003

Kauff Noah D, Brogi Edi, Scheuer Lauren, Pathak Dorothy R, Borgen Patrick I, Hudis Clifford A, Offit Kenneth, Robson Mark E

Abstract excerpt

BACKGROUND: It has been suggested that BRCA-associated breast carcinoma may often lack a detectable preinvasive phase. To investigate this hypothesis, the authors compared the prevalence of histopathologic lesions in prophylactic mastectomy (PM) specimens from women with BRCA mutations and in mastectomy specimens obtained at autopsy from an age and race-matched comparison group without a known cancer...

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Source

Identifiers

PMID: 12655515
DOI: 10.1002/cncr.11225

Genes

BRCA1
BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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