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Article

Prophylactic mastectomy in familial breast carcinoma. What do the pathologic findings learn us?

Breast cancer research and treatment - 1 Jan 2008

Leunen Karin, Drijkoningen Maria, Neven Patrick, Christiaens Maria-Rose, Van Ongeval Chantal, Legius Eric, Amant Frédéric, Berteloot Patrick, Vergote Ignace

Abstract excerpt

OBJECTIVE: To evaluate the indications, techniques and pathologic findings of prophylactic mastectomy (pME). METHODS: Retrospective study of patients with a strong family history of breast cancer (and ovarian cancer) or with proven BRCA mutation. RESULTS: Between January 1995 and December 2005, sixty seven patients underwent pME: 15% had a BRCA1 mutation, 31% had a BRCA2 mutation and 33% had a strong family...

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Source

Identifiers

PMID: 17431765
DOI: 10.1007/s10549-007-9525-8

Genes

BRCA1
BRCA2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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