Article
Examination of PPP1R3B as a candidate gene for the type 2 diabetes and MODY loci on chromosome 8p23.
Annals of human genetics - 1 Sept 2006
Dunn J S, Mlynarski W M, Pezzolesi M G, Borowiec M, Powers C, Krolewski A S, Doria A
Abstract excerpt
The product of the PPP1R3B gene (G(L)) is the regulatory subunit of PP1 - a serine/threonine phosphatase involved in the modulation of glycogen synthesis in the liver and skeletal muscle. The PPP1R3B gene is located on chromosome 8p23 in a region that has been linked with type 2 diabetes and matu...
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