Article
Candidate genes and late-onset type 2 diabetes mellitus. Susceptibility genes or common polymorphisms?
Danish medical bulletin - 1 Nov 2003
Hansen Lars
Abstract excerpt
Several lines of evidence suggest that the aetio-pathogenesis of the common form of type 2 diabetes mellitus and its intrinsically related features of impaired insulin secretion and decreased insulin sensitivity (insulin resistance) includes a strong genetic component. At present, however, little is known about the nature of this genetic component although familial clustering of the disease has been described for...
Topics
- Age of Onset
- Diabetes Mellitus, Type 2
- Genetic Predisposition to Disease
- Genotype
- Humans
- Insulin Resistance
- Mutation
