Article
Rhodopsin deactivation is affected by mutations of Tyrl91.
Photochemistry and photobiology - 1 Jan 2006
Lewis Margaret R, Kono Masahiro
Abstract excerpt
The 9-methyl group of 11-cis retinal is important in the efficient formation of the active conformation of rhodopsin, Meta II. Here, Tyrl91 rhodopsin mutants were generated because of its proximity to that methyl group in the dark structure. If photoactivation results in movement of the 9-methyl group toward Tyrl91, the steric interactions involved with activation and/or deactivation might not be as tightly...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.